Browsing by Author Nacci, Vito


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Issue DateTitleAuthor(s)Third Mission
1998Antiproliferative action of pyrrolobenzoxazepine derivatives in cultured cells: Absence of correlation with binding to the peripheral-type benzodiazepine binding siteDaniela M., Zisterer; Nicole, Hance; Campiani, Giuseppe ; Antonio, Garofalo; Nacci, Vito; D., Clive WilliamsNot applicable
1996An approach to modified heterocyclic analogues of huperzine A and isohuperzine A. Synthesis of the pyrimidone and pyrazole analogues, and their anticholinesterase activityAlan P., Kozikowski; Campiani, Giuseppe ; Nacci, Vito; Sega, Alessandro ; Ashima, Saxena; Bhupendra P., DoctorNot applicable
1993Benzothiazine and Benzothiazepine derivatives: synthesis and preliminary biological evaluationA., Garofalo; Campiani, Giuseppe ; Fiorini, Isabella; Nacci, VitoNot applicable
1996Cardiovascular Characterization of Pyrrolo[2,1-d][1,5]benzothiazepine Derivatives Binding Selectively to the Peripheral-Type Benzodiazepine Receptor (PBR):  From Dual PBR Affinity and Calcium Antagonist Activity to Novel and Selective Calcium Entry BlockersCampiani, Giuseppe ; Fiorini, Isabella; Maria P., De Filippis; Silvia M., Ciani; Antonio, Garofalo; Nacci, Vito; Giorgi, Gianluca ; Sega, Alessandro ; Botta, Maurizio ; Alberto, Chiarini; Roberta, Budriesi; Giancarlo, Bruni; Maria R., Romeo; Cristina, Manzoni; Tiziana, MenniniNot applicable
2002Caspase-3 is not essential for DNA fragmentation in MCF-7 cells during apoptosis induced by the pyrrolo-1,5-benzoxazepine, PBOX-6M., MC GEE; E., Hyland; Campiani, Giuseppe ; A., Ramunno; Nacci, Vito; Dm, ZistererNot applicable
2001Characterisation of 1H-cyclopentapyrimidine-2,4(1H,3H)-dione derivative (S)-CPW399 as a novel, potent and subtype-selective AMPA receptor full agonist with partial desensitization propertiesCampiani, Giuseppe ; E., Morelli; Nacci, Vito; C., Fattorusso; A., Ramunno; E., Novellino; J., Greenwood; T., Liljefors; R., Griffiths; C., Sinclair; H., Reavy; A. S., Kristensen; D. S., Pickering; A., Schousboe; A., Cagnotto; E., Fumagalli; T., MenniniNot applicable
2008Clotrimazole Scaffold as an Innovative Pharmacophore Towards Potent Antimalarial Agents: Design, Synthesis, Biological and Structure-Activity Relationship Studies.Gemma, Sandra ; Campiani, Giuseppe ; Butini, Stefania ; G., Kukreja; SANNA COCCONE, Salvatore; B., Joshi; M., Persico; Nacci, Vito; Fiorini, Isabella; E., Novellino; Fattorusso, E; O., TAGLIALATELA SCAFATI; Savini, Luisa; D., Taramelli; N., Basilico; S., Parapini; G., Morace; V., Yardley; S., Croft; M., Coletta; S., Marini; Fattorusso, CaterinaNot applicable
2009Combining 4-Aminoquinoline- and Clotrimazole-based Pharmacophores towards Innovative and Potent Hybrid Antimalarials.Gemma, Sandra ; Campiani, Giuseppe ; Butini, Stefania ; B. P., Joshi; G., Kukreja; SANNA COCCONE, Salvatore; Bernetti, Matteo; M., Persico; Nacci, Vito; Fiorini, Isabella; E., Novellino; D., Taramelli; N., Basilico; S., Parapini; V., Yardley; S., Croft; S., KELLER MAERKI; M., Rottmann; R., Brun; M., Coletta; S., Marini; G., Guiso; S., Caccia; C., FattorussoNot applicable
1994A Comparative Molecular Field Analysis Model for 6-Arylpyrrolo[2,1-d][1,5]benzothiazepines Binding Selectively to the Mitochondrial Benzodiazepine ReceptorGiovanni, Greco; Ettore, Novellino; Fiorini, Isabella; Nacci, Vito; Campiani, Giuseppe ; Silvia M., Ciani; Antonio, Garofalo; Paola, Bernasconi; Tiziana, MenniniNot applicable
1995A Concerted Study Using Binding Measurements, X-ray Structural Data, and Molecular Modeling on the Stereochemical Features Responsible for the Affinity of 6-Arylpyrrolo[2,1-d][1,5]benzothiazepines toward Mitochondrial Benzodiazepine ReceptorsAlessandro, Dalpiaz; Valerio, Bertolasi; Pier Andrea, Borea; Nacci, Vito; Fiorini, Isabella; Campiani, Giuseppe ; Tiziana, Mennini; Cristina, Manzoni; Ettore, Novellino; Giovanni, GrecoNot applicable
2007Design and Synthesis of Potent Antimalarial Agents Based on Clotrimazole Scaffold: Exploring an Innovative Pharmacophore.Gemma, Sandra ; Campiani, Giuseppe ; Butini, Stefania ; B., Joshi; G., Kukreja; M., Persico; B., Catalanotti; E., Novellino; Fattorusso, E; Nacci, Vito; Savini, Luisa; D., Taramelli; N., Basilico; G., Morace; V., Yardley; C., FattorussoNot applicable
2008Design, synthesis, and structure-activity relationship studies of 4-quinolinyl- and 9-acrydinylhydrazones as potent antimalarial agents.C., Fattorusso; Campiani, Giuseppe ; G., Kukreja; M., Persico; Butini, Stefania ; Romano, MARIA PIA; Altarelli, Maria; S., Ros; Brindisi, Margherita ; Savini, Luisa; E., Novellino; Nacci, Vito; E., Fattorusso; S., Parapini; N., Basilico; D., Taramelli; V., Yardley; S., Croft; M., Borriello; Gemma, Sandra Not applicable
2005Development of molecular probes for the identification of extra interaction sites in the mid-gorge and peripheral sites of butyrylcholinesterase (BuChE). Rational design of novel, selective, and highly potent BuChE inhibitors.Campiani, Giuseppe ; Fattorusso, C; Butini, Stefania ; Gaeta, A; Agnusdei, M; Gemma, Sandra ; Persico, M; Catalanotti, B; Savini, Luisa; Nacci, Vito; Novellino, E; Holloway, Hw; Greig, Nh; Belinskaya, T; Fedorko, Jm; Saxena, A.Not applicable
2009Discovery of a new class of potential multifunctional atypical antipsychotic agents targeting dopamine d3 and serotonin 5-HT 1A and 5-HT2A receptors: Design, synthesis, and effects on behaviorButini, Stefania ; Gemma, Sandra ; Campiani, Giuseppe ; Franceschini, Silvia; Trotta, Francesco; Marianna, Borriello; Nicoleta, Ceres; Sindu, Ros; SANNA COCCONE, Salvatore; Bernetti, Matteo; MERI DE, Angelis; Brindisi, Margherita ; Nacci, Vito; Fiorini, Isabella; Ettore, Novellino; Alfredo, Cagnotto; Tiziana, Mennini; KARIN SANDAGER, Nielsen; JESPER TOBIAS, Andreasen; JORGEN SCHEEL, Kruger; JENS D., Mikkelsen; AND CATERINA, FattorussoNot applicable
2006Discovery of Huperzine A/Tacrine Hybrids as Potent Inhibitors of Human Cholinesterases Targeting Their Mid-gorge Recognition SitesGemma, Sandra ; Gabellieri, Emanuele; Huleatt, P.; C., Fattorusso; M., Borriello; B., Catalanotti; Butini, Stefania ; M., DE ANGELIS; E., Novellino; Nacci, Vito; T., Belinskaya; Saxena, Ashima; Campiani, Giuseppe Not applicable
2008Exploiting Protein Fluctuations at the Active-Site Gorge of Human Cholinesterases: Further Optimization of the Design Strategy to Develop Extremely Potent InhibitorsButini, Stefania ; Campiani, Giuseppe ; M., Borriello; Gemma, Sandra ; Panico, Alessandro; M., Persico; B., Catalanotti; S., Ros; Brindisi, Margherita ; M., Agnusdei; Fiorini, Isabella; Nacci, Vito; E., Novellino; T., Belinskaya; A., Saxena; C., FattorussoNot applicable
2003Inhibition of G1 cyclin-dependent kinase activity during growth arrest of human astrocytoma cells by the pyrrolo-1,5-benzoxazepine, PBOX-21J. M., Mulligan; Campiani, Giuseppe ; A., Ramunno; Nacci, Vito; D. M., ZistererNot applicable
2003Neuronal high affinity sodium-dependent glutamate transporters (EAATs): targets for the development of novel therapeutics against neurodegenerative diseases.Campiani, Giuseppe ; Fattorusso, C.; DE ANGELIS, M.; Catalanotti, B.; Butini, Stefania ; Fattorusso, R.; Fiorini, Isabella; Nacci, Vito; Novellino, E.Not applicable
1998New Antipsychotic Agents with Serotonin and Dopamine Antagonist Properties Based on a Pyrrolo[2,1-b][1,3]benzothiazepine StructureCampiani, Giuseppe ; Nacci, Vito; Bechelli, Susanna ; Silvia M., Ciani; Antonio, Garofalo; Fiorini, Isabella; Håkan, Wikström; Peter de, Boer; Yi, Liao; Pieter G., Tepper; Alfredo, Cagnotto; Tiziana, MenniniNot applicable
1997New pyrrolobenzothiazepine derivatives as molecular probes of the ‘peripheral-type’ benzodiazepine receptor (PBR) binding siteCampiani, Giuseppe ; Nacci, Vito; Fiorini, Isabella; MP De, Filippis; A., Garofalo; Sm, Ciani; G., Greco; E., Novellino; C., Manzoni; T., MenniniNot applicable