Browsing by Author Luciani, Rosaria

Showing results 1 to 6 of 6
Issue DateTitleAuthor(s)Third Mission
20132'-Deoxyuridine 5'-monophosphate substrate displacement in thymidylate synthase through 6-hydroxy-2H-naphtho[1,8-bc]furan-2-one derivativesFerrari, Stefania; Calò, Samuele; Leone, Rosalida; Luciani, Rosaria; Costantino, Luca; Sammak, Susan; DI PISA, Flavio; Pozzi, Cecilia ; Mangani, Stefano ; Costi, M. PaolaNot applicable
2019Enhancement of Benzothiazoles as Pteridine Reductase-1 Inhibitors for the Treatment of Trypanosomatidic InfectionsLinciano, Pasquale; Pozzi, Cecilia ; Iacono, Lucia Dello; di Pisa, Flavio; Landi, Giacomo; Bonucci, Alessio; Gul, Sheraz; Kuzikov, Maria; Ellinger, Bernhard; Witt, Gesa; Santarem, Nuno; Baptista, Catarina; Franco, Caio; Moraes, Carolina B; Müller, Wolfgang; Wittig, Ulrike; Luciani, Rosaria; Sesenna, Antony; Quotadamo, Antonio; Ferrari, Stefania; Pöhner, Ina; Cordeiro-da-Silva, Anabela; Mangani, Stefano ; Costantino, Luca; Costi, Maria PaolaNot applicable
2017Exploiting the 2-Amino-1,3,4-thiadiazole Scaffold To Inhibit Trypanosoma brucei Pteridine Reductase in Support of Early-Stage Drug DiscoveryLinciano, Pasquale; Dawson, Alice; Pöhner, Ina; Costa, David M; Sá, Monica S; Cordeiro da silva, Anabela; Luciani, Rosaria; Gul, Sheraz; Witt, Gesa; Ellinger, Bernhard; Kuzikov, Maria; Gribbon, Philip; Reinshagen, Jeanette; Wolf, Markus; Behrens, Birte; Hannaert, Veronique; Michels, Paul A. M; Nerini, Erika; Pozzi, Cecilia ; DI PISA, Flavio; Landi, Giacomo; Santarem, Nuno; Ferrari, Stefania; Saxena, Puneet; Lazzari, Sandra; Cannazza, Giuseppe; Freitas junior, Lucio H; Moraes, Carolina B; Pascoalino, Bruno S; Alcântara, Laura M; Bertolacini, Claudia P; Fontana, Vanessa; Wittig, Ulrike; Müller, Wolfgang; Wade, Rebecca C; Hunter, William N; Mangani, Stefano ; Costantino, Luca; Costi, Maria PaolaNot applicable
2019Structural and functional characterization of the human thymidylate synthase (hTS) interface variant R175C, new perspectives for the development of hTS inhibitorsPozzi, Cecilia ; Ferrari, Stefania; Luciani, Rosaria; Costi, Maria Paola; Mangani, Stefano Not applicable
2019Structural comparison of enterococcus faecalis and human thymidylate synthase complexes with the substrate dUMP and its analogue FdUMP provides hints about enzyme conformational variabilitiesPozzi, Cecilia ; Ferrari, Stefania; Luciani, Rosaria; Tassone, Giusy ; Costi, Maria Paola; Mangani, Stefano Not applicable
2016X-ray crystal structures of Enterococcus faecalis thymidylate synthase with folate binding site inhibitorsCatalano, Alessia; Luciani, Rosaria; Carocci, Alessia; Cortesi, Debora; Pozzi, Cecilia ; Borsari, Chiara; Ferrari, Stefania; Mangani, Stefano Not applicable