Browsing by Author G., Maga

Showing results 1 to 16 of 16
Issue DateTitleAuthor(s)Third Mission
2010Crystal Structure of HIV-1 Reverse Transcriptase Bound to a Non-Nucleoside Inhibitor with a Novel Mechanism of ActionS., Freisz; G., Bec; Radi, Marco; P., Wolff; E., Crespan; Angeli, Lucilla; P., Dumas; G., Maga; Botta, Maurizio ; E., EnnifarNot applicable
2011Design, synthesis, biological activity and ADME properties of pyrazolo[3,4-d]pyrimidines active in hypoxic human leukemia cells: a lead optimization studyRadi, Marco; Dreassi, Elena ; C., Brullo; E., Crespan; Tintori, Cristina; V., Bernardo; Valoti, Massimo; Zamperini, Claudio; H., Daigl; F., Musumeci; Carraro, Fabio; Naldini, Antonella; Filippi, Irene; G., Maga; S., Schenone; Botta, Maurizio Not applicable
2010Dual Src and Abl inhibitors target wild type Abl and the AblT315I Imatinib-resistant mutant with different mechanismE., Crespan; Radi, Marco; S., Zanoli; S., Schenone; Botta, Maurizio ; G., MagaNot applicable
2004Effects of Drug Resistance Mutations L100I and V106A on the Binding of Pyrrolobenzoxazepinone Nonnucleoside Inhibitors to the Human Immunodeficiency Virus Type 1 Reverse Transcriptase Catalytic ComplexG. A., Locatelli; Campiani, Giuseppe ; R., Cancio; E., Morelli; A., Ramunno; Gemma, Sandra ; U., Hubscher; S., Spadari; G., MagaNot applicable
2010HIV-1 RT inhibitors with a novel mechanism of action: NNRTIs that compete with the nucleotide substrateG., Maga; Radi, Marco; M., Gerard; Botta, Maurizio ; E., EnnifarNot applicable
2008A Multidisciplinary Approach for the Identification ofNovel HIV-1 Non-Nucleoside Reverse TranscriptaseInhibitors: S-DABOCs and DAVPsRadi, Marco; Falciani, Chiara; Contemori, Lorenzo; Petricci, Elena ; G., Maga; A., Samuele; S., Zanoli; M., Terrazas; Castria, Marinunzia; Togninelli, Andrea; J. A., Esté; I., CLOTET CODINA; M., ARMAND UGON; Botta, Maurizio Not applicable
2008N-(thiazol-2-yl)-2-thiophene carboxamide derivatives as Abl inhibitors identified by a pharmacophore-based database screening of commercially available compoundsManetti, Fabrizio ; F., Falchi; E., Crespan; S., Schenone; G., Maga; Botta, Maurizio Not applicable
2002Non-Nucleoside HIV-1 Reverse Transcriptase (RT) Inhibitors: Past, Present, and Future PerspectivesCampiani, Giuseppe ; A., Ramunno; G., Maga; Nacci, Vito; C., Fattorusso; B., Catalanotti; E., Morelli; E., NovellinoNot applicable
2000Non-Nucleoside HIV-1 Reverse Transcriptase Inhibitors: Synthesis and Biological Evaluation of Novel Quinoxalinylethylpyridylthioureas as Potent Antiviral AgentsCampiani, Giuseppe ; Fabbrini, Monica; E., Morelli; Nacci, Vito; G., Greco; E., Novellino; G., Maga; S., Spadari; A., Bergamini; E., Faggioli; I., Uccella; F., Bolacchi; S., Marini; M., Coletta; C., Fracasso; S., CacciaNot applicable
2005Parallel Solution-Phase and Microwave-Assisted Synthesis of New S-DABO Derivatives Endowed with Subnanomolar Anti-HIV-1 ActivityManetti, Fabrizio ; J. A., Este; I., CLOTET CODINA; M., ARMAND UGON; G., Maga; E., Crespan; R., Cancio; Mugnaini, Claudia ; C., Bernardini; A., Togninelli; C., Carmi; M., Alongi; Petricci, Elena ; S., Massa; Corelli, Federico ; Botta, Maurizio Not applicable
2001Quinoxalinylethylpyridylthioureas (QXPTs) as Potent Non-nucleoside HIV-1 Reverse Transcriptase (RT) Inhibitors. Further SAR Studies and Identification of a Novel Orally Bioavailable Hydrazine-Based Antiviral AgentCampiani, Giuseppe ; F., Aiello; Fabbrini, Monica; E., Morelli; A., Ramunno; S., Armaroli; Nacci, Vito; A., Garofalo; G., Greco; E., Novellino; G., Maga; S., Spadari; A., Bergamini; L., Ventura; B., Bongiovanni; M., Capozzi; F., Bolacchi; S., Marini; M., Coletta; G., Guiso; S., CacciaNot applicable
2001Research on anti-HIV-1 agents. Part 2. Solid-phase synthesis, biological evaluation and molecular modeling studies of 2,5,6-trisubstituted-4(3H)-pyrimidinones targeting HIV-1 reverse transcriptaseBotta, Maurizio ; Corelli, Federico ; G., Maga; Manetti, Fabrizio ; M., Renzulli; S., SpadariNot applicable
2008Selective targeting of the HIV-1 reverse transcriptase catalytic complex through interaction with the ‘‘primer grip’’ region by pyrrolobenzoxazepinone non-nucleoside inhibitors correlates with increased activity towards drug-resistant mutants.S., Zanoli; Gemma, Sandra ; Butini, Stefania ; Brindisi, Margherita ; B. P., Joshi; Campiani, Giuseppe ; C., Fattorusso; M., Persico; E., Crespan; R., Cancio; S., Spadari; U., Hubscher; G., MagaNot applicable
1998Solid Phase Synthesis of 2,6-Disubstituted-4(3H)-pyrimidinones Targeting HIV-1 Reverse TranscriptaseE., Nizi; Botta, Maurizio ; Corelli, Federico ; Manetti, Fabrizio ; F., Messina; G., MagaNot applicable
2005Specific Targeting of Hepatitis C Virus NS3 RNA Helicase. Discovery of the Potent and Selective Competitive Nucleotide-Mimicking Inhibitor QU663G., Maga; Gemma, Sandra ; C., Fattorusso; G. A., Locatelli; Butini, Stefania ; M., Persico; G., Kukreja; Romano, MARIA PIA; Chiasserini, Luisa ; Savini, Luisa; E., Novellino; Nacci, Vito; S., Spadari; Campiani, Giuseppe Not applicable
2001The Stereoselective Targeting of a Specific Enzyme-Substrate Complex is the Molecular Mechanism for the Synergic Inhibition of HIV-1 Reverse Transcriptase by (R)-(-)PPO464, a Novel Generation of Non-Nucleoside InhibitorsG., Maga; A., Ramunno; Nacci, Vito; G., Locatelli; S., Spadari; F., Baldanti; S., Paolucci; M., Zavattoni; A., Bergamini; B., Galletti; S., Muck; U., Hubscher; Giorgi, Gianluca ; G., Guiso; S., Caccia; Campiani, Giuseppe Not applicable