Browsing by Author Fiorini, Isabella


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Issue DateTitleAuthor(s)Third Mission
20081H-Cyclopentapyrimidine-2,4(1H,3H)-dione-Related Ionotropic Glutamate Receptors Ligands. Structure-Activity Relationships and Identification of Potent and Selective iGluR5 ModulatorsButini, Stefania ; DARRYL S., Pickering; Elena, Morelli; SANNA COCCONE, Salvatore; Trotta, Francesco; MERI DE, Angelis; Guarino, Egeria; Fiorini, Isabella; Campiani, Giuseppe ; Ettore, Novellino; Arne, Schousboe; JEPPE K., Christensen; Gemma, Sandra Not applicable
1993Benzothiazine and Benzothiazepine derivatives: synthesis and preliminary biological evaluationA., Garofalo; Campiani, Giuseppe ; Fiorini, Isabella; Nacci, VitoNot applicable
1996Cardiovascular Characterization of Pyrrolo[2,1-d][1,5]benzothiazepine Derivatives Binding Selectively to the Peripheral-Type Benzodiazepine Receptor (PBR):  From Dual PBR Affinity and Calcium Antagonist Activity to Novel and Selective Calcium Entry BlockersCampiani, Giuseppe ; Fiorini, Isabella; Maria P., De Filippis; Silvia M., Ciani; Antonio, Garofalo; Nacci, Vito; Giorgi, Gianluca ; Sega, Alessandro ; Botta, Maurizio ; Alberto, Chiarini; Roberta, Budriesi; Giancarlo, Bruni; Maria R., Romeo; Cristina, Manzoni; Tiziana, MenniniNot applicable
2008Clotrimazole Scaffold as an Innovative Pharmacophore Towards Potent Antimalarial Agents: Design, Synthesis, Biological and Structure-Activity Relationship Studies.Gemma, Sandra ; Campiani, Giuseppe ; Butini, Stefania ; G., Kukreja; SANNA COCCONE, Salvatore; B., Joshi; M., Persico; Nacci, Vito; Fiorini, Isabella; E., Novellino; Fattorusso, E; O., TAGLIALATELA SCAFATI; Savini, Luisa; D., Taramelli; N., Basilico; S., Parapini; G., Morace; V., Yardley; S., Croft; M., Coletta; S., Marini; Fattorusso, CaterinaNot applicable
2009Combining 4-Aminoquinoline- and Clotrimazole-based Pharmacophores towards Innovative and Potent Hybrid Antimalarials.Gemma, Sandra ; Campiani, Giuseppe ; Butini, Stefania ; B. P., Joshi; G., Kukreja; SANNA COCCONE, Salvatore; Bernetti, Matteo; M., Persico; Nacci, Vito; Fiorini, Isabella; E., Novellino; D., Taramelli; N., Basilico; S., Parapini; V., Yardley; S., Croft; S., KELLER MAERKI; M., Rottmann; R., Brun; M., Coletta; S., Marini; G., Guiso; S., Caccia; C., FattorussoNot applicable
1994A Comparative Molecular Field Analysis Model for 6-Arylpyrrolo[2,1-d][1,5]benzothiazepines Binding Selectively to the Mitochondrial Benzodiazepine ReceptorGiovanni, Greco; Ettore, Novellino; Fiorini, Isabella; Nacci, Vito; Campiani, Giuseppe ; Silvia M., Ciani; Antonio, Garofalo; Paola, Bernasconi; Tiziana, MenniniNot applicable
1995A Concerted Study Using Binding Measurements, X-ray Structural Data, and Molecular Modeling on the Stereochemical Features Responsible for the Affinity of 6-Arylpyrrolo[2,1-d][1,5]benzothiazepines toward Mitochondrial Benzodiazepine ReceptorsAlessandro, Dalpiaz; Valerio, Bertolasi; Pier Andrea, Borea; Nacci, Vito; Fiorini, Isabella; Campiani, Giuseppe ; Tiziana, Mennini; Cristina, Manzoni; Ettore, Novellino; Giovanni, GrecoNot applicable
2009Discovery of a new class of potential multifunctional atypical antipsychotic agents targeting dopamine d3 and serotonin 5-HT 1A and 5-HT2A receptors: Design, synthesis, and effects on behaviorButini, Stefania ; Gemma, Sandra ; Campiani, Giuseppe ; Franceschini, Silvia; Trotta, Francesco; Marianna, Borriello; Nicoleta, Ceres; Sindu, Ros; SANNA COCCONE, Salvatore; Bernetti, Matteo; MERI DE, Angelis; Brindisi, Margherita ; Nacci, Vito; Fiorini, Isabella; Ettore, Novellino; Alfredo, Cagnotto; Tiziana, Mennini; KARIN SANDAGER, Nielsen; JESPER TOBIAS, Andreasen; JORGEN SCHEEL, Kruger; JENS D., Mikkelsen; AND CATERINA, FattorussoNot applicable
2010Discovery of Bishomo(hetero)arylpiperazines as Novel Multifunctional Ligands Targeting Dopamine D-3 and Serotonin 5-HT1A and 5-HT2A ReceptorsButini, Stefania ; Campiani, Giuseppe ; Franceschini, Silvia; Trotta, Francesco; Kumar, V; Guarino, Egeria; Borrelli, Giuseppe; Fiorini, Isabella; Novellino, E; Fattorusso, C; Persico, M; Orteca, N; SANDAGER NIELSEN, K; Jacobsen, Ta; Madsen, K; SCHEEL KRUGER, J; Gemma, Sandra Not applicable
2011Discovery of potent nucleotide-mimicking competitive inhibitors of hepatitis C virus NS3 helicaseGemma, Sandra ; Butini, Stefania ; Campiani, Giuseppe ; Brindisi, Margherita ; Samantha, Zanoli; Romano, MARIA PIA; Tripaldi, Pierangela; Savini, Luisa; Fiorini, Isabella; Borrelli, Giuseppe; Ettore, Novellino; Giovanni, MagaNot applicable
2008An efficient approach to chiral C8/C9-Piperazino-Substituted 1,4-Benzodiazepin-2-ones as peptidomimetic scaffoldsButini, Stefania ; Gabellieri, Emanuele; PAUL BRADY, Huleatt; Campiani, Giuseppe ; Franceschini, Silvia; Brindisi, Margherita ; Sindu, Ros; SANNA COCCONE, Salvatore; Fiorini, Isabella; Ettore, Novellino; Giorgi, Gianluca ; Gemma, Sandra Not applicable
2011Enantioselective binding of second generation pyrrolobenzoxazepinones to the catalytic ternary complex of HIV-1 RT wild-type and L100I and K103N drug resistant mutantsButini, Stefania ; Gemma, Sandra ; Brindisi, Margherita ; Borrelli, Giuseppe; Fiorini, Isabella; Alberta, Samuele; Aristotele, Karytinos; Marcella, Facchini; Andrea, Lossani; Samantha, Zanoli; Campiani, Giuseppe ; Ettore, Novellino; Federico, Focher; Giovanni, MagaNot applicable
2008Exploiting Protein Fluctuations at the Active-Site Gorge of Human Cholinesterases: Further Optimization of the Design Strategy to Develop Extremely Potent InhibitorsButini, Stefania ; Campiani, Giuseppe ; M., Borriello; Gemma, Sandra ; Panico, Alessandro; M., Persico; B., Catalanotti; S., Ros; Brindisi, Margherita ; M., Agnusdei; Fiorini, Isabella; Nacci, Vito; E., Novellino; T., Belinskaya; A., Saxena; C., FattorussoNot applicable
2012Mimicking the Intramolecular Hydrogen Bond: Synthesis, Biological Evaluation, and Molecular Modeling of Benzoxazines and Quinazolines as Potential Antimalarial AgentsGemma, Sandra ; Camodeca, Caterina; Brindisi, Margherita ; Brogi, Simone; Gagan, Kukreja; Kunjir, SANIL ASHOK; Emanuele, Gabellieri; Leonardo, Lucantoni; Annette, Habluetzel; Donatella, Taramelli; Nicoletta, Basilico; Roberta, Gualdani; Francesco Tadini, Buoninsegni; Gianluca, Bartolommei; Maria Rosa, Moncelli; Rowena E., Martin; Robert L., Summers; Lamponi, Stefania ; Savini, Luisa; Fiorini, Isabella; Valoti, Massimo; Ettore, Novellino; Campiani, Giuseppe ; Butini, Stefania Not applicable
2003Neuronal high affinity sodium-dependent glutamate transporters (EAATs): targets for the development of novel therapeutics against neurodegenerative diseases.Campiani, Giuseppe ; Fattorusso, C.; DE ANGELIS, M.; Catalanotti, B.; Butini, Stefania ; Fattorusso, R.; Fiorini, Isabella; Nacci, Vito; Novellino, E.Not applicable
1998New Antipsychotic Agents with Serotonin and Dopamine Antagonist Properties Based on a Pyrrolo[2,1-b][1,3]benzothiazepine StructureCampiani, Giuseppe ; Nacci, Vito; Bechelli, Susanna ; Silvia M., Ciani; Antonio, Garofalo; Fiorini, Isabella; Håkan, Wikström; Peter de, Boer; Yi, Liao; Pieter G., Tepper; Alfredo, Cagnotto; Tiziana, MenniniNot applicable
1997New pyrrolobenzothiazepine derivatives as molecular probes of the ‘peripheral-type’ benzodiazepine receptor (PBR) binding siteCampiani, Giuseppe ; Nacci, Vito; Fiorini, Isabella; MP De, Filippis; A., Garofalo; Sm, Ciani; G., Greco; E., Novellino; C., Manzoni; T., MenniniNot applicable
2011Non-Nucleoside Inhibitors of Human Adenosine Kinase: Synthesis, Molecular Modeling, and Biological StudiesButini, Stefania ; Gemma, Sandra ; Brindisi, Margherita ; Borrelli, Giuseppe; Andrea, Lossani; ANNA MARIA, Ponte; Andrea, Torti; Giovanni, Maga; Luciana, Marinelli; VALERIA LA, Pietra; Fiorini, Isabella; Lamponi, Stefania ; Campiani, Giuseppe ; DANIELA M., Zisterer; SEEMA MARIA, Nathwani; Stefania, Sartini; CONCETTINA LA, Motta; FEDERICO DA, Settimo; Ettore, Novellino; Federico, FocherNot applicable
2003Novel antipsychotic agents: recent advances in the drug treatment of schizophreniaButini, Stefania ; Campiani, Giuseppe ; M., DE ANGELIS; C., Fattorusso; Nacci, Vito; Fiorini, IsabellaNot applicable
2005Novel atypical antipsychotic agents: rational design, an efficient palladium-catalyzed route, and pharmacological studiesCampiani, Giuseppe ; Butini, Stefania ; C., Fattorusso; F., Trotta; Gemma, Sandra ; B., Catalanotti; Nacci, Vito; Fiorini, Isabella; A., Cagnotto; I., Mereghetti; T., Mennini; P., Minetti; M. A., DI CESARE; M. A., Stasi; S., DI SERIO; O., Ghirardi; O., Tinti; P., CarminatiNot applicable