Browsing by Author E., Novellino

Showing results 1 to 19 of 19
Issue DateTitleAuthor(s)Third Mission
2001Characterisation of 1H-cyclopentapyrimidine-2,4(1H,3H)-dione derivative (S)-CPW399 as a novel, potent and subtype-selective AMPA receptor full agonist with partial desensitization propertiesCampiani, Giuseppe ; E., Morelli; Nacci, Vito; C., Fattorusso; A., Ramunno; E., Novellino; J., Greenwood; T., Liljefors; R., Griffiths; C., Sinclair; H., Reavy; A. S., Kristensen; D. S., Pickering; A., Schousboe; A., Cagnotto; E., Fumagalli; T., MenniniNot applicable
2008Clotrimazole Scaffold as an Innovative Pharmacophore Towards Potent Antimalarial Agents: Design, Synthesis, Biological and Structure-Activity Relationship Studies.Gemma, Sandra ; Campiani, Giuseppe ; Butini, Stefania ; G., Kukreja; SANNA COCCONE, Salvatore; B., Joshi; M., Persico; Nacci, Vito; Fiorini, Isabella; E., Novellino; Fattorusso, E; O., TAGLIALATELA SCAFATI; Savini, Luisa; D., Taramelli; N., Basilico; S., Parapini; G., Morace; V., Yardley; S., Croft; M., Coletta; S., Marini; Fattorusso, CaterinaNot applicable
2009Combining 4-Aminoquinoline- and Clotrimazole-based Pharmacophores towards Innovative and Potent Hybrid Antimalarials.Gemma, Sandra ; Campiani, Giuseppe ; Butini, Stefania ; B. P., Joshi; G., Kukreja; SANNA COCCONE, Salvatore; Bernetti, Matteo; M., Persico; Nacci, Vito; Fiorini, Isabella; E., Novellino; D., Taramelli; N., Basilico; S., Parapini; V., Yardley; S., Croft; S., KELLER MAERKI; M., Rottmann; R., Brun; M., Coletta; S., Marini; G., Guiso; S., Caccia; C., FattorussoNot applicable
2007Design and Synthesis of Potent Antimalarial Agents Based on Clotrimazole Scaffold: Exploring an Innovative Pharmacophore.Gemma, Sandra ; Campiani, Giuseppe ; Butini, Stefania ; B., Joshi; G., Kukreja; M., Persico; B., Catalanotti; E., Novellino; Fattorusso, E; Nacci, Vito; Savini, Luisa; D., Taramelli; N., Basilico; G., Morace; V., Yardley; C., FattorussoNot applicable
2008Design, synthesis, and structure-activity relationship studies of 4-quinolinyl- and 9-acrydinylhydrazones as potent antimalarial agents.C., Fattorusso; Campiani, Giuseppe ; G., Kukreja; M., Persico; Butini, Stefania ; Romano, MARIA PIA; Altarelli, Maria; S., Ros; Brindisi, Margherita ; Savini, Luisa; E., Novellino; Nacci, Vito; E., Fattorusso; S., Parapini; N., Basilico; D., Taramelli; V., Yardley; S., Croft; M., Borriello; Gemma, Sandra Not applicable
2006Discovery of Huperzine A/Tacrine Hybrids as Potent Inhibitors of Human Cholinesterases Targeting Their Mid-gorge Recognition SitesGemma, Sandra ; Gabellieri, Emanuele; Huleatt, P.; C., Fattorusso; M., Borriello; B., Catalanotti; Butini, Stefania ; M., DE ANGELIS; E., Novellino; Nacci, Vito; T., Belinskaya; Saxena, Ashima; Campiani, Giuseppe Not applicable
2008Exploiting Protein Fluctuations at the Active-Site Gorge of Human Cholinesterases: Further Optimization of the Design Strategy to Develop Extremely Potent InhibitorsButini, Stefania ; Campiani, Giuseppe ; M., Borriello; Gemma, Sandra ; Panico, Alessandro; M., Persico; B., Catalanotti; S., Ros; Brindisi, Margherita ; M., Agnusdei; Fiorini, Isabella; Nacci, Vito; E., Novellino; T., Belinskaya; A., Saxena; C., FattorussoNot applicable
2003Inherent desensitisation-preventing properties of a novel, subtype-selective AMPA receptor agonist, (S)-CPW399 as a possible explanation for its excitotoxic action in cultured cerebellar granule cellsC., Sinclair; H., Reavy; A., Grieve; A., Schousboe; E., Morelli; E., Novellino; Campiani, Giuseppe ; R., GriffithsNot applicable
2011New Insight into the Central Benzodiazepine Receptor-Ligand Interactions: Design, Synthesis, Biological Evaluation, and Molecular Modeling of 3-Substituted 6-Phenyl-4H-imidazo[1,5-a][1,4]benzodiazepines and Related CompoundsAnzini, Maurizio ; S., Valenti; C., Braile; Cappelli, Andrea ; Vomero, Salvatore; S., Alcaro; F., Ortuso; L., Marinelli; V., Limongelli; E., Novellino; L., Betti; G., Giannaccini; A., Lucacchini; S., Daniele; C., Martini; C., Ghelardini; L., DI CESARE MANNELLI; Giorgi, Gianluca ; M. P., Mascia; G., BiggioNot applicable
1997New pyrrolobenzothiazepine derivatives as molecular probes of the ‘peripheral-type’ benzodiazepine receptor (PBR) binding siteCampiani, Giuseppe ; Nacci, Vito; Fiorini, Isabella; MP De, Filippis; A., Garofalo; Sm, Ciani; G., Greco; E., Novellino; C., Manzoni; T., MenniniNot applicable
2002Non-Nucleoside HIV-1 Reverse Transcriptase (RT) Inhibitors: Past, Present, and Future PerspectivesCampiani, Giuseppe ; A., Ramunno; G., Maga; Nacci, Vito; C., Fattorusso; B., Catalanotti; E., Morelli; E., NovellinoNot applicable
2000Non-Nucleoside HIV-1 Reverse Transcriptase Inhibitors: Synthesis and Biological Evaluation of Novel Quinoxalinylethylpyridylthioureas as Potent Antiviral AgentsCampiani, Giuseppe ; Fabbrini, Monica; E., Morelli; Nacci, Vito; G., Greco; E., Novellino; G., Maga; S., Spadari; A., Bergamini; E., Faggioli; I., Uccella; F., Bolacchi; S., Marini; M., Coletta; C., Fracasso; S., CacciaNot applicable
2005Pyrrolo[1,5]benzoxa(thia)zepines as a New Class of Potent Apoptotic Agents. Biological Studies and Identification of an Intracellular Location of Their Drug TargetM. M., MC GEE; Gemma, Sandra ; Butini, Stefania ; A., Ramunno; D. M., Zisterer; C., Fattorusso; B., Catalanotti; G., Kukreja; Fiorini, Isabella; C., Pisano; C., Cucco; E., Novellino; Nacci, Vito; D. C., Williams; Campiani, Giuseppe Not applicable
1999Pyrroloquinoxaline Derivatives as High-Affinity and Selective 5-HT3 Receptor Agonists: Synthesis, Further Structure-Activity Relationships, and Biological StudiesCampiani, Giuseppe ; E., Morelli; Gemma, Sandra ; Nacci, Vito; Butini, Stefania ; M., Hamon; E., Novellino; G., Greco; A., Cagnotto; M., Goegan; L., Cervo; F., DALLA VALLE; C., Fracasso; S., Caccia; T., MenniniNot applicable
2001Quinoxalinylethylpyridylthioureas (QXPTs) as Potent Non-nucleoside HIV-1 Reverse Transcriptase (RT) Inhibitors. Further SAR Studies and Identification of a Novel Orally Bioavailable Hydrazine-Based Antiviral AgentCampiani, Giuseppe ; F., Aiello; Fabbrini, Monica; E., Morelli; A., Ramunno; S., Armaroli; Nacci, Vito; A., Garofalo; G., Greco; E., Novellino; G., Maga; S., Spadari; A., Bergamini; L., Ventura; B., Bongiovanni; M., Capozzi; F., Bolacchi; S., Marini; M., Coletta; G., Guiso; S., CacciaNot applicable
2001A rational approach to the design of selective substrates and potent non-transportable inhibitors of the excitatory amino acid transporter EAAC1 (EAAT3). New glutamate and aspartate analogues as potential neuroprotective agents.Campiani, Giuseppe ; M., De Angelis; S., Armaroli; C., Fattorusso; B., Catalanotti; A., Ramunno; Nacci, Vito; E., Novellino; C., Grewer; D., Ionescu; T., Rauen; R., Griffiths; C., Sinclair; E., Fumagalli; T., MenniniNot applicable
2005Specific Targeting of Hepatitis C Virus NS3 RNA Helicase. Discovery of the Potent and Selective Competitive Nucleotide-Mimicking Inhibitor QU663G., Maga; Gemma, Sandra ; C., Fattorusso; G. A., Locatelli; Butini, Stefania ; M., Persico; G., Kukreja; Romano, MARIA PIA; Chiasserini, Luisa ; Savini, Luisa; E., Novellino; Nacci, Vito; S., Spadari; Campiani, Giuseppe Not applicable
2008Synthesis, Cannabinoid Receptor Affinity, and Molecular Modeling Studies of Substituted 1-Aryl-5-(1H-pyrrol-1-yl)-1H-pyrazole-3-carboxamides.R., Silvestri; M. G., Cascio; G., LA REGINA; G., Piscitelli; G., Lavecchia; Brizzi, Antonella ; Pasquini, Serena; Botta, Maurizio ; E., Novellino; V., DI MARZO; Corelli, Federico Not applicable
2008Tacrine based human cholinesterase inhibitors: synthesis of peptidic-tethered derivatives and their effects on potency and selectivityButini, Stefania ; Guarino, Egeria; Campiani, Giuseppe ; Brindisi, Margherita ; SANNA COCCONE, Salvatore; Fiorini, Isabella; E., Novellino; T., Belinskaya; A., Saxena; Gemma, Sandra Not applicable