Browsing by Author Brogi, Simone


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Issue DateTitleAuthor(s)Third Mission
20133D-QSAR using pharmacophore-based alignment and virtual screening for discovery of novel MCF-7 cell line inhibitorsBrogi, Simone; Panagiota, Papazafiri; Vassilios, Roussis; Tafi, Andrea Not applicable
2017Activation of the Wnt pathway by small peptides: rational design, synthesis and biological evaluationBrogi, Simone; Maramai, Samuele ; Brindisi, Margherita ; Chemi, Giulia ; Porcari, Valentina; Corallo, Claudio; Gennari, Luigi; Novellino, Ettore; Ramunno, Anna; Butini, Stefania ; Campiani, Giuseppe ; Gemma, Sandra Not applicable
2019Allosteric Modulation of Ionotropic Glutamate Receptors: An Outlook on New Therapeutic Approaches To Treat Central Nervous System DisordersBrogi, Simone; Campiani, Giuseppe ; Brindisi, Margherita ; Butini, Stefania Not applicable
2018Antimalarial agents against both sexual and asexual parasites stages: structure-activity relationships and biological studies of the Malaria Box compound 1-[5-(4-bromo-2-chlorophenyl)furan-2-yl]- N -[(piperidin-4-yl)methyl]methanamine (MMV019918) and analoguesVallone, Alessandra; D'Alessandro, Sarah; Brogi, Simone; Brindisi, Margherita ; Chemi, Giulia ; Alfano, Gloria; Lamponi, Stefania ; Lee, Soon Goo; Jez, Joseph M.; Koolen, Karin J. M.; Dechering, Koen J.; Saponara, Simona; Fusi, Fabio ; Gorelli, Beatrice; Taramelli, Donatella; Parapini, Silvia; Caldelari, Reto; Campiani, Giuseppe ; Gemma, Sandra ; Butini, Stefania Not applicable
2012Characterization of COR627 and COR628, two novel positive allosteric modulators of the GABA B receptorCastelli, M. P.; Casu, A.; Casti, P.; Lobina, C.; Carai, M. A. M.; Colombo, G.; Solinas, M.; Giunta, D.; Mugnaini, Claudia ; Pasquini, Serena; Tafi, Andrea ; Brogi, Simone; Gessa, G. L.; Corelli, Federico Not applicable
2019Cinnamic acids derived compounds with antileishmanial activity target Leishmania amazonensis arginaseda Silva, Edson Roberto; Brogi, Simone; Grillo, Alessandro; Campiani, Giuseppe ; Gemma, Sandra ; Vieira, Paulo Cezar; Maquiaveli, Claudia do CarmoNot applicable
2017Computational tool for fast in silico evaluation of hERG K+ channel affinityChemi, Giulia ; Gemma, Sandra ; Campiani, Giuseppe ; Brogi, Simone; Butini, Stefania ; Brindisi, Margherita Not applicable
2012Design, Synthesis, and Pharmacological Characterization of Indole-3-ylacetamides, Indole-3-yloxoacetamides, and Indole-3-ylcarboxamides: Potent and Selective CB2 Cannabinoid Receptor Inverse AgonistsPasquini, Serena; Mugnaini, Claudia ; Ligresti, A.; Tafi, Andrea ; Brogi, Simone; Falciani, C.; Pedani, Valentina; Pesco, N.; Guida, F.; Luongo, L.; Varani, K.; Borea, P. A.; Maione, S.; Di Marzo, V.; Corelli, Federico Not applicable
2016Development and Pharmacological Characterization of Selective Blockers of 2-Arachidonoyl Glycerol Degradation with Efficacy in Rodent Models of Multiple Sclerosis and PainBrindisi, Margherita ; Maramai, Samuele ; Gemma, Sandra ; Brogi, Simone; Grillo, Alessandro; Di Cesare Mannelli, Lorenzo; Gabellieri, Emanuele; Lamponi, Stefania ; Saponara, Simona; Gorelli, Beatrice; Tedesco, Daniele; Bonfiglio, Tommaso; Landry, Christophe; Jung, Kwang Mook; Armirotti, Andrea; Luongo, Livio; Ligresti, Alessia; Piscitelli, Fabiana; Bertucci, Carlo; Dehouck, Marie Pierre; Campiani, Giuseppe ; Maione, Sabatino; Ghelardini, Carla; Pittaluga, Anna; Piomelli, Daniele; Di Marzo, Vincenzo; Butini, Stefania Not applicable
2015Development of HuperTacrines as non-toxic, cholinesterase inhibitors for the potential treatment of Alzheimer's diseaseChioua, Mourad; Pérez, Marta; Bautista-Aguilera, Oscar M; Yañez, Matilde; López, Manuela G; Romero, Alejandro; Cacabelos, Ramón; de la Bellacasa, Raimon Puig; Brogi, Simone; Butini, Stefania ; Borrell, José I; Marco-Contelles, JoseNot applicable
2016Development of novel cyclic peptides as pro-apoptotic agentsBrindisi, Margherita ; Maramai, Samuele ; Brogi, Simone; Fanigliulo, Emanuela; Butini, Stefania ; Guarino, Egeria; Casagni, Alice; Lamponi, Stefania ; Bonechi, Claudia ; Nathwani, Seema M; Finetti, Federica ; Ragonese, Francesco; Arcidiacono, Paola; Campiglia, Pietro; Valenti, Salvatore; Novellino, Ettore; Spaccapelo, Roberta; Morbidelli, Lucia; Zisterer, Daniela M; Williams, Clive D; Donati, Alessandro ; Baldari, Cosima; Campiani, Giuseppe ; Ulivieri, Cristina; Gemma, Sandra Not applicable
2018Development of Potent Inhibitors of Fatty Acid Amide Hydrolase Useful for the Treatment of Neuropathic PainBrindisi, Margherita ; Borrelli, Giuseppe; Brogi, Simone; Grillo, Alessandro; Maramai, Samuele ; Paolino, Marco ; Benedusi, Mascia; Pecorelli, Alessandra; Valacchi, Giuseppe; Di Cesare Mannelli, Lorenzo; Ghelardini, Carla; Allarà, Marco; Ligresti, Alessia; Minetti, Patrizia; Campiani, Giuseppe ; Butini, Stefania ; di Marzo, Vincenzo; Gemma, Sandra Not applicable
2018Development of Potent Inhibitors of the Mycobacterium tuberculosis Virulence Factor Zmp1 and Evaluation of Their Effect on Mycobacterial Survival inside MacrophagesPaolino, Marco ; Brindisi, Margherita ; Vallone, Alessandra; Butini, Stefania ; Campiani, Giuseppe ; Nannicini, Chiara; Giuliani, Germano ; Anzini, Maurizio ; Lamponi, Stefania ; Giorgi, Gianluca ; Sbardella, Diego; Ferraris, Davide M; Marini, Stefano; Coletta, Massimo; Palucci, Ivana; Minerva, Mariachiara; Delogu, Giovanni; Pepponi, Ilaria; Goletti, Delia; Cappelli, Andrea ; Gemma, Sandra ; Brogi, SimoneNot applicable
2014Discovery of GPCR ligands for probing signal transduction pathwaysBrogi, Simone; Tafi, Andrea ; Désaubry, Laurent; Nebigil, CananNot applicable
2014Disease modifying anti-Alzheimer’s drugs: inhibitors of human cholinesterases interfering with β-amyloid aggregationBrogi, Simone; Butini, Stefania ; Maramai, Samuele ; Raffaella, Colombo; Laura, Verga; Cristina, Lanni; Ersilia De, Lorenzi; Lamponi, Stefania ; Andreassi, Marco ; Manuela, Bartolini; Vincenza, Andrisano; Ettore, Novellino; Campiani, Giuseppe ; Brindisi, Margherita ; Gemma, Sandra Not applicable
2016Donepezil-like multifunctional agents: Design, synthesis, molecular modeling and biological evaluationWu, Ming-Yu; Esteban, Gerard; Brogi, Simone; Shionoya, Masahi; Wang, Li; Campiani, Giuseppe ; Unzeta, Mercedes; Inokuchi, Tsutomu; Butini, Stefania ; Marco-Contelles, JoseNot applicable
2015Exploring clotrimazole-based pharmacophore: 3D-QSAR studies and synthesis of novel antiplasmodial agentsBrogi, Simone; Brindisi, Margherita ; Joshi, Bhupendra P.; Sanna Coccone, Salvatore; Parapini, Silvia; Basilico, Nicoletta; Novellino, Ettore; Campiani, Giuseppe ; Gemma, Sandra ; Butini, Stefania Not applicable
2017First dual AK/GSK-3β inhibitors endowed with antioxidant properties as multifunctional, potential neuroprotective agentsBrogi, Simone; Ramunno, Anna; Savi, Lida; Chemi, Giulia ; Alfano, Gloria; Pecorelli, Alessandra; Pambianchi, Erika; Galatello, Paola; Compagnoni, Giulia; Focher, Federico; Biamonti, Giuseppe; Valacchi, Giuseppe; Butini, Stefania ; Gemma, Sandra ; Campiani, Giuseppe ; Brindisi, Margherita Not applicable
2014From (+)-epigallocatechin gallate to a simplified synthetic analogue as a cytoadherence inhibitor for P. falciparumGemma, Sandra ; Brogi, Simone; Pradeep R., Patil; Giovani, Simone; Lamponi, Stefania ; Cappelli, Andrea ; Ettore, Novellino; Alan, Brown; Matthew K., Higgins; Khairul, Mustafa; Tadge, Szestak; Alister G., Craig; Campiani, Giuseppe ; Butini, Stefania ; Brindisi, Margherita Not applicable
2016Harnessing the pyrroloquinoxaline scaffold for FAAH and MAGL interaction: Definition of the structural determinants for enzyme inhibitionBrindisi, Margherita ; Brogi, Simone; Maramai, Samuele ; Grillo, Alessandro; Borrelli, Giuseppe; Butini, Stefania ; Novellino, Ettore; Allarà, Marco; Ligresti, Alessia; Campiani, Giuseppe ; Di Marzo, Vincenzo; Gemma, Sandra Not applicable