Browsing by Author Chemi, Giulia


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Issue DateTitleAuthor(s)Third Mission
2017Activation of the Wnt pathway by small peptides: rational design, synthesis and biological evaluationBrogi, Simone; Maramai, Samuele ; Brindisi, Margherita ; Chemi, Giulia ; Porcari, Valentina; Corallo, Claudio; Gennari, Luigi; Novellino, Ettore; Ramunno, Anna; Butini, Stefania ; Campiani, Giuseppe ; Gemma, Sandra Not applicable
2018Antimalarial agents against both sexual and asexual parasites stages: structure-activity relationships and biological studies of the Malaria Box compound 1-[5-(4-bromo-2-chlorophenyl)furan-2-yl]- N -[(piperidin-4-yl)methyl]methanamine (MMV019918) and analoguesVallone, Alessandra; D'Alessandro, Sarah; Brogi, Simone; Brindisi, Margherita ; Chemi, Giulia ; Alfano, Gloria; Lamponi, Stefania ; Lee, Soon Goo; Jez, Joseph M.; Koolen, Karin J. M.; Dechering, Koen J.; Saponara, Simona; Fusi, Fabio ; Gorelli, Beatrice; Taramelli, Donatella; Parapini, Silvia; Caldelari, Reto; Campiani, Giuseppe ; Gemma, Sandra ; Butini, Stefania Not applicable
2019Bridged bicyclic 2,3-dioxabicyclo[3.3.1]nonanes as antiplasmodial agents: Synthesis, structure-activity relationships and studies on their biomimetic reaction with Fe(II)D'Alessandro, S.; Alfano, G.; Di Cerbo, L.; Brogi, S.; Chemi, Giulia ; Relitti, Nicola ; Brindisi, Margherita ; Lamponi, Stefania ; Novellino, E.; Campiani, Giuseppe ; Gemma, Sandra ; Basilico, N.; Taramelli, D.; Baratto, Maria Camilla ; Pogni, Rebecca ; Butini, Stefania Not applicable
2017Computational tool for fast in silico evaluation of hERG K+ channel affinityChemi, Giulia ; Gemma, Sandra ; Campiani, Giuseppe ; Brogi, Simone; Butini, Stefania ; Brindisi, Margherita Not applicable
2019Development of novel multipotent compounds modulating endocannabinoid and dopaminergic systemsGrillo, A.; Chemi, Giulia ; Brogi, S.; Brindisi, Margherita ; Relitti, Nicola ; Fezza, F.; Fazio, D.; Castelletti, L.; Perdona, E.; Wong, A.; Lamponi, Stefania ; Pecorelli, A.; Benedusi, M.; Fantacci, M.; Valoti, M.; Valacchi, G.; Micheli, F.; Novellino, E.; Campiani, Giuseppe ; Butini, Stefania ; Maccarrone, M.; Gemma, Sandra Not applicable
2017First dual AK/GSK-3β inhibitors endowed with antioxidant properties as multifunctional, potential neuroprotective agentsBrogi, Simone; Ramunno, Anna; Savi, Lida; Chemi, Giulia ; Alfano, Gloria; Pecorelli, Alessandra; Pambianchi, Erika; Galatello, Paola; Compagnoni, Giulia; Focher, Federico; Biamonti, Giuseppe; Valacchi, Giuseppe; Butini, Stefania ; Gemma, Sandra ; Campiani, Giuseppe ; Brindisi, Margherita Not applicable
2019Identification of Novel 3-Hydroxy-pyran-4-One Derivatives as Potent HIV-1 Integrase Inhibitors Using in silico Structure-Based Combinatorial Library Design ApproachSirous, Hajar; Chemi, Giulia ; Gemma, Sandra ; Butini, Stefania ; Debyser, Zeger; Christ, Frauke; Saghaie, Lotfollah; Brogi, Simone; Fassihi, Afshin; Campiani, Giuseppe ; Brindisi, Margherita Not applicable
2016Identification of novel fluorescent probes preventing PrP(Sc) replication in prion diseasesZaccagnini, Ludovica; Brogi, Simone; Brindisi, Margherita ; Gemma, Sandra ; Chemi, Giulia ; Legname, Giuseppe; Campiani, Giuseppe ; Butini, Stefania Not applicable
2020Ionotropic Glutamate Receptor GluA2 in Complex with Bicyclic Pyrimidinedione-Based Compounds: When Small Compound Modifications Have Distinct Effects on Binding InteractionsFrydenvang, Karla; Pickering, Darryl S; Kshirsagar, Giridhar U; Chemi, Giulia ; Gemma, Sandra ; Sprogøe, Desiree; Kærn, Anne Mette; Brogi, Simone; Campiani, Giuseppe ; Butini, Stefania ; Kastrup, Jette SandholmNot applicable
2018A Jocic-type approach for a practical and scalable synthesis of pyrrolonaphthoxazepine (PNOX)-based potent proapoptotic agentsFederico, Stefano ; Khan, Tuhina ; Relitti, Nicola ; Chemi, Giulia ; Brindisi, Margherita ; Brogi, Simone; Novellino, Ettore; Zisterer, Daniela M.; Campiani, Giuseppe ; Gemma, Sandra ; Butini, Stefania Not applicable
2019A light in the dark: State of the art and perspectives in optogenetics and optopharmacology for restoring visionChemi, Giulia ; Brindisi, Margherita ; Brogi, S.; Relitti, Nicola ; Butini, Stefania ; Gemma, Sandra ; Campiani, Giuseppe Not applicable
2020Novel quinolone-based potent and selective HDAC6 inhibitors: Synthesis, molecular modeling studies and biological investigationRelitti, Nicola ; Saraswati, A. P.; Chemi, Giulia ; Brindisi, Margherita ; Brogi, S.; Herp, D.; Schmidtkunz, K.; Saccoccia, F.; Ruberti, G.; Ulivieri, C.; Vanni, F.; Sarno, F.; Altucci, L.; Lamponi, Stefania ; Jung, M.; Gemma, Sandra ; Butini, Stefania ; Campiani, Giuseppe Not applicable
2018Novel spiroindoline HDAC inhibitors: Synthesis, molecular modelling and biological studiesBrindisi, Margherita ; Senger, Johanna; Cavella, Caterina; Grillo, Alessandro; Chemi, Giulia ; Gemma, Sandra ; Cucinella, Dora Mariagrazia; Lamponi, Stefania ; Sarno, Federica; Iside, Concetta; Nebbioso, Angela; Novellino, Ettore; Shaik, Tajith Baba; Romier, Christophe; Herp, Daniel; Jung, Manfred; Butini, Stefania ; Campiani, Giuseppe ; Altucci, Lucia; Brogi, SimoneNot applicable
2019A repurposing approach for uncovering the anti-tubercular activity of FDA-approved drugs with Potential Multi-Targeting ProfilesBattah, B.; Chemi, Giulia ; Butini, Stefania ; Campiani, Giuseppe ; Brogi, S.; Delogu, G.; Gemma, Sandra Not applicable
2018(S)-2-Amino-3-(5-methyl-3-hydroxyisoxazol-4-yl)propanoic Acid (AMPA) and Kainate Receptor Ligands: further exploration of bioisosteric replacements and structural and biological investigationBrogi, Simone; Brindisi, Margherita ; Butini, Stefania ; Kshirsagar, Giridhar U.; Maramai, Samuele ; Chemi, Giulia ; Gemma, Sandra ; Campiani, Giuseppe ; Novellino, Ettore; Fiorenzani, Paolo; Pinassi, Jessica; Aloisi, Anna Maria; Gynther, Mikko; Venskutonytė, Raminta; Han, Liwei; Frydenvang, Karla; Kastrup, Jette Sandholm; Pickering, Darryl S.Not applicable
2020Screening and Phenotypical Characterization of Schistosoma mansoni Histone Deacetylase 8 (SmHDAC8) Inhibitors as Multistage Antischistosomal AgentsSaccoccia, F.; Brindisi, Margherita ; Gimmelli, R.; Relitti, Nicola ; Guidi, A.; Saraswati, A. P.; Cavella, C.; Brogi, S.; Chemi, Giulia ; Butini, Stefania ; Papoff, G.; Senger, J.; Herp, D.; Jung, M.; Campiani, Giuseppe ; Gemma, Sandra ; Ruberti, G.Not applicable
2020Spiroindoline-Capped Selective HDAC6 Inhibitors: Design, Synthesis, Structural Analysis, and Biological EvaluationSaraswati, A Prasanth; Relitti, Nicola ; Brindisi, Margherita ; Osko, Jeremy D; Chemi, Giulia ; Federico, Stefano ; Grillo, Alessandro; Brogi, Simone; McCabe, Niamh H; Turkington, Richard C; Ibrahim, Ola; O'Sullivan, Jeffrey; Lamponi, Stefania ; Ghanim, Magda; Kelly, Vincent P; Zisterer, Daniela; Amet, Rebecca; Hannon Barroeta, Patricia; Vanni, Francesca; Ulivieri, Cristina; Herp, Daniel; Sarno, Federica; Di Costanzo, Antonella; Saccoccia, Fulvio; Ruberti, Giovina; Jung, Manfred; Altucci, Lucia; Gemma, Sandra ; Butini, Stefania ; Christianson, David W; Campiani, Giuseppe Not applicable
2017Structural characterization of Giardia duodenalis thioredoxin reductase (gTrxR) and computational analysis of its interaction with NBDHEXBrogi, Simone; Fiorillo, Annarita; Chemi, Giulia ; Butini, Stefania ; Lalle, Marco; Ilari, Andrea; Gemma, Sandra ; Campiani, Giuseppe Not applicable
2019Structure-activity relationships, biological evaluation and structural studies of novel pyrrolonaphthoxazepines as antitumor agentsBrindisi, Margherita ; Ulivieri, Cristina; Alfano, Gloria; Gemma, Sandra ; de Asís Balaguer, Francisco; Khan, Tuhina ; Grillo, Alessandro; Chemi, Giulia ; Menchon, Grégory; Prota, Andrea E; Olieric, Natacha; Lucena-Agell, Daniel; Barasoain, Isabel; Diaz, J Fernando; Nebbioso, Angela; Conte, Mariarosaria; Lopresti, Ludovica ; Magnano, Stefania; Amet, Rebecca; Kinsella, Paula; Zisterer, Daniela M; Ibrahim, Ola; O'Sullivan, Jeff; Morbidelli, Lucia; Spaccapelo, Roberta; Baldari, Cosima; Butini, Stefania ; Novellino, Ettore; Campiani, Giuseppe ; Altucci, Lucia; Steinmetz, Michel O; Brogi, SimoneNot applicable
2019Synthesis, biological evaluation and molecular modeling of novel selective COX-2 inhibitors: sulfide, sulfoxide, and sulfone derivatives of 1,5-diarylpyrrol-3-substituted scaffoldReale, Annalisa ; Brogi, S.; Chelini, A.; Paolino, Marco ; Di Capua, A.; Giuliani, Germano ; Cappelli, Andrea ; Giorgi, Gianluca ; Chemi, Giulia ; Grillo, A.; Valoti, M.; Sautebin, L.; Rossi, A.; Pace, S.; La Motta, C.; Di Cesare Mannelli, L.; Lucarini, E.; Ghelardini, C.; Anzini, Maurizio Not applicable